B.Sc. in Organic Chemistry, Department
of Chemistry, Qufu Normal University,
P. R. China
since 09/2001
M.S. student, DDDC, Chinese Academy of Sciences,
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RESEARCH
This study is aimed
at characterization of the structure and the structure-activity
relationships of FXR, to construct human FXR LBD model and further
to define a series of likely effective agonists or antagonists.
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This
picture shows the pocket of the LBD of the nuclear receptor FXR
and the agonist CDCA lying in the middle of the pocket.