Curriculum Vitae
1. Education:
1982 - 1986 Grundschule in Birkenfeld/Nahe, Germany
1986 - 1994 Gymnasium in Birkenfeld/Nahe, Germany
1991 Jump from the 9th into the 10th grade
10.6. 1994 Allgemeine Hochschulreife (grade 1.2)
10/1994 Undergraduate studies in chemistry at the University of Kaiserslautern, Germany
21.10. 1996 Diplom-Vorpr邦fung (grade 1.2)
10/1996 每 7/1997 Wissenschaftliche Hilfskraft (faculty for chemistry, University
and 9/1998 of Kaiserslautern)
10/1998 每 7/1999 Wissenschaftliche Hilfskraft (Institut f邦r Techno- und Wirtschaftsmathematik Kaiserslautern)
10/1999 每 3/2000 External diploma thesis "Calculation of Binding Free Energies" in Biocomputing (Prof. J.C. Smith) at the interdisciplinary center for scientific computing (IWR) at the University of Heidelberg, Germany (grade 1.0)
28.3. 2000 Diplom (final grade 1.3)
4 每 9/2000 Undergraduate studies in mathematics at the University of Heidelberg
since 10/2000 PhD studies "Understanding the ATP Hydrolysis Mechanism in Myosin Using Computer Simulation Techniques" at the IWR (Prof. J. C. Smith)
1/2001 每 3/2002 Postgraduate studies in bioinformatics at the „Akademie f邦r Weiterbildung der Universitäten Heidelberg und Mannheim※ (grade very good)
2. Practicals and projects:
1995 Project „Citynetz Kaiserslautern※ within „Modellversuch Interdisziplinäres Studienprogramm※
10/1996 Practical at the Computer-Chemistry-Center of the University Erlangen-N邦rnberg
7 每 10/1997 Summer Internship at Procter&Gamble GmbH in Schwalbach/Ts
10/1997 每 1/1998 Internship at F. Hoffmann-La Roche AG in Basel/Switzerland
4 每 8/1998 Research practical at the University of Edinburgh/Great Britain
3 每 6/2005 Guest Scientist at the Shanghai Institute of Materia Medica, Drug Discovery and Design Center
3. Awards and Scholarships:
1989 2. price „Wettbewerb Mathematik Rheinland-Pfalz※
1991 1. price „Tag der Mathematik Universität Kaiserslautern※
1993 2. price „Regionalwettbewerb Jugend Forscht※
2/1997 Procter&Gamble Studienförderpreis an der Universität Kaiserslautern for best Vordiplom
2/1997 Scholarship of the „Studienstiftung des deutschen Volkes※ for
undergraduate studies
10/2000 每 9/2003 PhD scholarship of Boehringer Ingelheim Fonds
10/2000 每 9/2003 PhD scholarship of the „Studienstiftung des deutschen Volkes※
2001 Scholarship of the Klaus-Tschira-Stiftung for postgraduate studies in Bioinformatics.
since 2002 E-fellows scholarship
12/2004 [i]lab award of the [i]lab initiative, Aventis Pharma Deutschland GmbH
3 每 6/2005 Visiting scientest scholarship of EMBO/CAS world programme
4. Memberships:
since 1995 Gesellschaft Deutscher Chemiker
Fachgruppe Chemie - Information 每 Computer
Arbeitskreis Chancengleichheit in der Chemie (AKCC)
since 1/2003 Board member of AKCC
since 2003 American Chemical Society
5. Publications:
5.1. Reviewed Publications
1) R.O. Gould, C. Dick, F.J.J. Dijksma, S. Parsons, S. Schwarzl, P. Taylor and M. Walkingshaw. Packing motifs in strychnine crystals. Acta Crystallogr., Sect. A, 55 (1999), S391.
2) E. Vilsmaier, W. Roth, W. Eisfeld, A. Preis, U. Bergsträßer, R. Philipp, S. Schwarzl, K. Schmadel and M. Magnano. Morpholino-azahomotricyclanimines 每 morpholine derivatives with a bulky cage-type substituent. J. Mol. Struct. 513 (1999), 117 - 126.
3) S. M. Schwarzl, T. B. Tschopp, J. C. Smith, S. Fischer. Can the calculation of binding free energies be improved with continuum electrostatics and an ideal-gas entropy correction? J. Comput. Chem. 23 (2002), 1143-1149.
4) A. Tournier, D. Huang, S. M. Schwarzl, S. Fischer, J. C. Smith. Time-resolved computational protein biochemistry: solvent effects on interactions, conformational transitions and equilibrium fluctuations. Faraday Disc. 122 (2002), 243-251.
5) S. M. Schwarzl, D. Huang, J. C. Smith, S. Fischer. How well does charge reparametrisation account for solvent screening in molecular mechanics calculations? The example of myosin. In Silico Biology 3 (2003), 187-196.
6) F. Noe, S. M. Schwarzl, S. Fischer, J. Smith. Computational tools for analyzing structural changes in proteins in solution. Applied Bioinformatics 2 (2003), S11-S17.
7) T. Efferth, E. B. Bachli, S. M. Schwarzl, J. Goede, C. West, J. C. Smith, E. Beutler. Glucose-6-phosphate dehydrogenase (G6PD)-deficiency type Zurich: a splice site mutation as novel mechanism of enzyme inactivation. Blood 104 (2004), 1.
8) F. Meyer, S. M. Schwarzl, T. Tschopp, A. Dejaegere, J. C. Smith, S. Fischer Binding free energies calculated with quantum mechanics/molecular mechanics. J. Phys. Chem. B. In press.
9) S. M. Schwarzl, J. C. Smith, B. Kaina, T. Efferth. Molecular model of O6-methylguanine methyltransferase harboring single nucleotide polymorphism-related amino acid changes. Accepted.
10) S. M. Schwarzl, D. Huang, J. C. Smith, S. Fischer. Non-Uniform Charge Scaling (NUCS): fast implicit-solvent electrostatic screening in macromolecules. Submitted.
11) S. M. Schwarzl, J. C. Smith, S. Fischer. QM/MM simulations of ATP hydrolysis in myosin: new insight into the chemomechanical coupling in molecular motors. In preparation.
12) S. M. Schwarzl, A.-N. Bondar, J. C. Smith, S. Fischer. Criterion of usefulness applied to a link-atom method for combined quantum mechanical/molecular mechanical calculations. In preparation.
5. 2. Book chapters
1) U. Ernst, W. Gollmann, P. von Loewis, N. Röthlingshöfer und S. Schwarzl. Citynetz Kaiserslautern. In Virtuelle Welten und Teleworking: Herausforderungen 每 Chancen 每 Risiken, E. Zwierlein, R. Isenmann (Hrsg.), Shaker Verlag Aachen 1998.
2) A. Gruß, S. M. Schwarzl (eds.) Chemikerinnen 每 es gab und es gibt sie. Brosch邦re des AK Chancengleichheit in der Chemie zum Jahr der Chemie 2003.
3) S. M. Schwarzl, S. Fischer, J.C. Smith. Solvent electrostatic screening in protein simulations. In: Bioinformatics of Genome Regulation and Structure, N. Kolchanov and R. Hofestädt (eds.), Kluwer Academic Publishers 2004, 179-184.
4) S. M. Schwarzl. Equal opportunity in chemistry in Germany. In: Dissolving Disparity, Catalyzing Change: Are Women Achieving Equity in Chemistry? C. H. Marzabadi, V. J. Kuck, S. Nolan, J. P. Buckner (eds.), ACS Symposium Series Book. In press.
5.3. Additional publications
1) S. M. Schwarzl, W. Wunderlich. Zum Beispiel: Clara Immerwahr. Nachrichten aus der Chemie 49 (2001), 407 - 408.
2) S. M. Schwarzl, W. Wunderlich. Zum Beispiel: Margarete von Wrangell. Nachrichten aus der Chemie 49 (2001), 824 - 825.
3) S. M. Schwarzl, W. Wunderlich, A. Kruse, S. Servaty. Zum Beispiel: Erika Cremer. Nachrichten aus der Chemie 49 (2001), 1106 - 1108.
4) S. M. Schwarzl, S. Servaty, A. Kruse. Zum Beispiel: Margot Becke-Goehring. Nachrichten aus der Chemie 50 (2002), 77 - 78.
5) S. M. Schwarzl, M. Hertel. Zum Beispiel: Liselotte Feikes. Nachrichten aus der Chemie 50 (2002), 639 - 640.
6) A. Kruse, S. M. Schwarzl. Zum Beispiel: Agnes Pockels. Nachrichten aus der Chemie 50 (2002), 759 - 760.
7) S. M. Schwarzl, M. Hertel. Zum Beispiel: Edith Weyde Nachrichten aus der Chemie 50 (2002), 1283 - 1284.
8) S. M. Schwarzl. Zum Beispiel: Marika Geldmacher-von Mallinckrodt. Nachrichten aus der Chemie 51 (2003), 732 - 733.
9) S. M. Schwarzl. Zum Beispiel: Helga Kersten. Nachrichten aus der Chemie, 51 (2003), 977 - 980.
10) S. M. Schwarzl. Chemisches Ungleichgewicht. Karrieref邦hrer Chemie, 2. Jahrgang 2004/2005, 18 每 19.
11) S. M. Schwarzl. Gleiche Chancen in der Chemie? Ein Überblick 邦ber Daten und Fakten als Beitrag zur öffentlichen Diskussion. Eine Veröffentlichung des AKCC, Sektion in der GDCh. In preparation.
6. Conferences and Workshops
4.-6.12. 2000 2. Treffen des DFG Schwerpunktprogramms Molekulare Motoren, Heidelberg
1.-3.4. 2001 Annual Meeting of the GDCh Fachgruppe CIC, Leipzig (invited talk)
23.-24.5. 2001 H邦nfeld Workshop "Computer Simulation and Theory of Biomolecules" der deutschen biophysikalischen Gesellschaft (invited talk)
3.-8.9. 2001 Boehringer Ingelheim Fonds scholarship meeting, Hirschegg, Germany (invited talk)
25.-27.1. 2002 ESS meeting "Protein dynamics and function", Heidelberg (organisation and poster presentation)
21.2.-27.2. 2002 46th annual meeting of the biophysical society and satellite meeting Peter Kollman memorial symposium, San Francisco, USA (poster presentation)
12.-13.4. 2002 H邦nfeld Workshop "Computer Simulation and Theory of Biomolecules" (poster presentation)
20.6. 2002 Building Protein-Protein Interaction Networks in Heidelberg, EML Heidelberg
14.-20.7. 2002 Third international conference on bioinformatics of genome regulation and structure, Novosibirsk, Russia (invited talk)
31.7.-4.8. 2002 Studienstiftung scholarship meeting, Wittenberg, Germany
30.9.-2.10. 2002 ※Promoting Younger Chemists§ conference, Heidelberg
6.-12.10. 2002 Boehringer Ingelheim Fonds scholarship meeting, Hirschegg, Germany (invited talk)
14.-16.10. 2002 Franco-German graduate college workshop ※Structural bioinformatics and structural biology§, Heidelberg (invited talk)
6.-7.2. 2003 Challenges in Biophysics Symposium, Heidelberg
23.-27.3. 2003 225th National Meeting of the American Chemical Society, New Orleans
9.-12.4. 2003 Doctoral and postdoctoral research symposium in biomolecular simulation, Ringberg Castle (invited talk)
4.-5.9. 2003 Visit at MIT, Boston (invited talk), USA
6.-11.9. 2003 226th National Meeting of the American Chemical Society, New York (invited talk and poster presentation)
5.-8.7. 2004 Workshop ※Mathematical Cell Biology§, Heidelberg
19.-21.9. 2004 International Symposium on retinal proteins: experiments and theory, DKFZ Heidelberg (poster presentation)
15.10. 2004 Symposium ※100 Jahre Frauen an deutschen technischen Hochschulen※, TH Karlsruhe (poster presentation)
24.-28.5. 2005 Visit at Institute of Botany, Chinese Academy of Sciences, Kunming, China (invited talk)
3.-8.7. 2005 Gordon Research Conference ※Muscle: contractile proteins※, New London, USA (poster presentation)
